Hoover left the Spartans' 14-0 win against Purdue last Saturday in the second half and defensive line coach Ron Burton said he is "a little nicked up."
"We'll see as the week progresses as far as that situation occurs," he said. "But he is limping around a little bit but that's part of the game."
The sixth-year senior is second on the team with 3.5 sacks this season, but Burton said leadership will be an area he would be missed.
"It would be a loss because he's a sixth-year senior with a lot of experience up front," he said. "He's a true leader in the defensive line and he will continue to be, but we got a bunch of guys.
"We're playing five so there'll be four guys that are raring to get the position."
The fourth player would be Lawrence Thomas, who still has yet to see the field as he works back from an injury.