In a big of a schedule oddity, the Spartans and Hoosiers are meeting for the second time this season Tuesday.
It is the first time this season a pair of Big Ten teams has played twice and it presents advantages and challenges.
"You prefer it as far as preparation," coach Tom Izzo said, "but you don't prefer it because, everybody says, well you beat them by 15 down there, whatever we beat them by, so you should just beat them again.
"Where time lapses, so many things happen that can change that."
The Spartans actually beat the Hoosiers by 17 in a 73-56 win in Bloomington.
Sophomore Gary Harris had a season-high 26 points in the game to lead MSU. He said the short time between the two games makes the Hoosiers "fresh" in their minds.
"They are going to be ready to play and try to get revenge after we beat them on their home court," he said. "They are going to come and they are going to be ready. It's going to be a battle."
"It's kind of confusing," forward Kenny Kaminski said. "They're kind of an up-and-down team and that's what makes them dangerous. Wisconsin is a great team and they beat them. I watched that game and I was really impressed with them.
"They've really improved since the last time we've seen them."
Senior guard Keith Appling said it always is tough to beat the same team twice, especially after the way they won at Indiana in early January.
"I'm pretty sure we are going to get their best shot and we are going to have to stay focused for 40 minutes," he said.