Auburn's defensive effort combined with a 42-32 rebounding edge was too much for UTC to deal with on a night the Tigers shot 41.2 percent from the field.
Sophomore guard Hasina Muhammad, the SEC Player of the Week, led all scorers with 19 points while adding five rebounds and three steals.
Senior forward Blanche Alverson produced a double-double with 11 points and 10 rebounds. The rebounds total matched Alverson's career high set last season vs. Mercer.
Freshman center Tra'cee Tanner came off the bench to chip in with nine points and seven rebounds while her sister Tyrese Tanner, a junior guard/forward, added eight rebounds and five points.
UTC, which fell to 8-2 for the season, was led by Ashlen Dewart's 13 points.
The visitors' strategy to attack Auburn with three-point shots was ineffective as UTC launched 31 while making just four.
"I think the difference in the game was us getting out and contesting the shooters," Alverson said. "That was something we put a lot of emphasis on in practice because they had been shooting the ball very well and averaging around 75 points per game."
Auburn won the game despite struggles with its three-point shooting and free throws. The Tigers were 1-9 on treys and hit just 10-19.
"It wasn't the prettiest of wins, but we will take it," said Auburn coach Terri Williams-Flournoy, whose team jumped out to a 19-4 advantage at the 11:16 mark of the first half and led by double figures much of the night.
The Lady Mocs cut the lead to 32-25 at the 14:37 mark of the second half, but Auburn built its advantage back to 15 points on a jump shot by Alverson with 7:08 to play and coasted in with the win.
Auburn returns to action Saturday at 2 p.m. with a home game vs. Jacksonville State.