USC starter Chris Spigner gave up three hits and a walk and left the game before recording an out. Jason Burkley doubled in two runs and Steve Gendron drove in another run with an infield groundout that staked MSU starter Joey Collums to a 3-1 first-inning edge.
USC added a run in the third and chased Collums (1-1) from the game two batters deep into the fourth. Buscher opened the inning with a double to right and Trey Dyson walked. Jacob Blakeney then replaced Collums, and was greeted by Landon Powell's run-scoring single to center field. Two batters later Meyer unloaded his roundtripper and the Bulldogs were never able to catch up.
Junior lefty Steven Bondurant (2-0), retired the three batters he faced after replacing Spigner in the first, worked around a lead-off triple by Chad Henry in the third and gave up a run on a walk and an RBI single by Matthew Maniscalco in the fourth.
Bondurant, too, ran into difficulties in the fifth when Jason Burkley, Jon Mungle and pinch hitter/second baseman Josh Thoms delivered back-to-back singles to score a run. Bondurant left the game with two out and two runners on base, and his replacement, Tony Adler, walked the next two Bulldog batters to plate MSU's second run in the inning and pull State within a run at 6-5. Adler ended the Bulldog rally when he got Maniscalco to ground out with the bases loaded to end the inning. He combined with Blake Taylor to blank the Bulldogs over the final 3-1/3 innings. Taylor earned his fourth save of the year and second in as many days, retiring five of the six Bulldog batters he faced in the eighth and ninth.
Meyer, Peters, Powell and Justin Harris had two hits each for USC while the Bulldogs got a three-hit performance from Chad Henry and two-hit showings by Maniscalco and Burkley.
Brian Owens, Ryan Carroll and Steven Dowe pitched in the final three innings for Mississippi State.
The Bulldogs conclude their four-game homestand Wednesday, hosting Mississippi Valley State in a 6:30 p.m. game at Dudy Noble Field. Next weekend Mississippi State travels to Lexington, Ky., for a three-game SEC series against the Kentucky Wildcats.
SOUTH CAROLINA 9, MISSISSIPPI STATE 6
USC (18-3, 2-1 SEC) 101 411 001 - 9-12-0
MSU (10-6-1, 1-2 SEC) 300 120 000 - 6-10-1
WP - Steven Bondurant (2-0). LP - Joey Collums (1-1). SV - Blake Taylor (4). HR - (USC) Drew Meyer (2), Yaron Peters (9). T - 2:57. ATT - 6,037 (paid), 1,459 (actual).