The Wolfpack and Hoyas were tied at 37 at the break, but Austin Freeman and Chris Wright led Georgetown during a second half when NC State's inexperience showed.
Richard Howell led NC State with 14 points and eight rebounds off the bench and was named to the all-tournament team. Only two other players -- Lorenzo Brown and DeShawn Painter -- scored in double figures. Brown scored 11 and added five rebounds while Painter picked up 10 and seven.
Georgetown was led by Hollis Thompson's 18 points and nine rebounds and had four players in double figures. Preseason Big East Player of the Year Austin Freeman scored 15.
NC State started strong, building a six point lead six minutes into the game, and found itself tied with the Hoyas at halftime.
The Wolfpack took a 44-42 lead with 16:30 left in the second, but it would be NC State's final lead of the game. A 15-0 run by Georgetown put the Hoyas up 57-42 at the 11-minute mark and ended NC State's chances of starting the season 4-0. During the Georgetown run NC State missed seven shots (four from behind the arc) and turned the ball over twice.
The Wolfpack shot 39.7 percent from the field and made just four of its 17 three point attempts. NC State's offense struggled at times without senior forward Tracy Smith, who left the ECU Thursday with a knee injury and had surgery Friday. Smith is expected to miss three weeks and should be back by mid-December.
NC State finished the game with 10 turnovers and tallied just eight assists on its 25 made baskets. The Hoyas finished the game 45 percent from the field and had 21 assists on 32 made field goals. Georgetown out-rebounded NC State 42-33.
Georgetown point guard Chris Wright, a former NC State commit, scored 17 points and dished out seven assists.
NC State returns home Saturday for a match-up with Fairleigh Dickinson at the RBC Center. Tip-off is set for 6 p.m.