The Wolfpack, the No. 1 seed, finished 39-17 overall and open bracket play taking on No. 4 seed Sacred Heart (25-30). In the other game, No. 2 seed Vanderbilt (33-26) takes on No. 3 seed UNC Wilmington (38-21).
Winners will square off and losers in the double-elimination regional.
The winner of the Raleigh Regional will face the winner of the Gainesville Regional that features: No. 1 seed Florida, No. 2 seed Georgia Tech, No. 3 seed Charleston, No. 4 seed Bethune-Cookman.