Freshman Maverick Rowan added 20 points for the Wolfpack (13-12, 3-9 Atlantic Coast Conference) in a matchup of teams near the bottom of the league standings. N.C. State avenged last month's road loss that stood as Wake Forest's only league win, shooting 54 percent after halftime and getting to the line 45 times for the game.
And Barber once again put on another show, the kind that has made him the ACC's leading scorer. He finished 10 for 20 from the floor and 17 for 20 on free throws, getting to the line 18 times after halftime alone.
Codi Miller-McIntyre scored a season-high 24 points for the Demon Deacons (10-15, 1-12), while Devin Thomas had 15 points and a career-high 21 rebounds.
But Wake Forest lost for the 10th straight time since beating N.C. State 77-74 on Jan. 10, and pushed its school-record ACC road losing streak to 21 games.
It was also the 11th straight loss for Wake Forest in Raleigh. The Demon Deacons haven't won here since an infamous game in 2005 when future NBA all-star Chris Paul popped Wolfpack star Julius Hodge in the groin after a rebound in the first half - missed by the referees but later leading to a one-game suspension - then hit the winning shot at the buzzer on an ugly night in Raleigh.
Barber came in averaging 23.5 points per game to rank sixth nationally, though he had upped his numbers over the last five to average 28.4 points on 54 percent shooting from the field and 52 percent from 3-point range.
He took over in the second half on Saturday, befuddling a defense that was incapable of keeping him from going to the rim, getting to the foul line or doing just about anything else he wanted to do.
The point guard got plenty of help too. In addition to Rowan, Caleb Martin added 18 points and seven rebounds. And N.C. State finished with 17 points off turnovers, rallying from an early 10-point deficit and stretching the lead out in the final minutes at the line to seal it.
Wake Forest: Bryant Crawford scored 16 points. ... Wake Forest shot 56 percent in the first half but just 41 percent after halftime. ... Wake Forest's last ACC road win was at Virginia Tech in January 2014, according to STATS.
N.C. State: N.C. State shot 50 percent for the game and made 33 of 45 free throws (73 percent), including 24 of 31 (77 percent) in the second half. ...Abdul-Malik Abu had four blocks.
Wake Forest travels to Pittsburgh on Tuesday.
N.C. State travels to No. 7 Virginia on Monday.