Question One: Brian Kelly praised Dayne Crist for his growth the day he was named Notre Dame's starting quarterback. Can Crist deliver on the field and fulfill Kelly's trust in leading the Irish to a strong opening showing?
Question Two: Several freshmen could take the field for their first official game in a Irish uniform. Will first game jitters lead to mistakes that will hurt the Irish on the field?
Question Three: The Irish defense ended the 2011 season with several solid performances. Can Bob Diaco's unit continue to perform as it did in the final month last season; now nine months later against a very athletic South Florida?
Question Five: Brian Kelly loves to throw the football, and while the running game had its moments in November 2010, there was still work to be done. Will the Irish running game get off to a strong start against the stout rush defense of the Bulls?