Fellow freshman Nemanja Djurisic added 10 points for the Bulldogs (4-1), who rebounded nicely from a rout at the hands of No. 20 California to escape Kansas City with some positive vibes.
The young Bulldogs built a seven-point lead early in the second half, but the Irish (4-2) tied it at 53 with 5:11 to play on two free throws by Jerian Grant.
Caldwell-Pope broke the tie with his fourth 3-pointer of the game with 3:37 left, and added a free throw moments later to give the Bulldogs a four-point cushion. Georgia prevented Notre Dame from making another field goal until Grant's 3-pointer at the buzzer.