North Carolina at Indiana, Ohio State at Duke, and North Carolina State at Michigan will highlight the two-day tournament set for Nov. 27-28. All six programs will likely be highly ranked heading into the 2012-13 season.
ESPN, ESPN2, ESPNU and ESPN3.com will televise all 12 games of the two-day event, though times and specific networks have yet to be announced.
Ohio State beat Duke in the Challenge in Columbus last year, 85-63, in a matchup that featured two of the country's top three teams.
"The game last year in Columbus had two perennial top college basketball programs battle each other in an extraordinary environment," OSU coach Thad Matta said in a release. "I expect something very similar when the Buckeyes travel to Duke this November."
Matta has posted a 5-3 record in the event and has led the Buckeyes to wins in each of the last four Challenge games. The Buckeyes, who boast a 6-5 record in the event, last lost to North Carolina at home on Nov. 29, 2007.
Ohio State and Duke have played six times and each team has won three games. However, the Buckeyes trip to Duke will make for the team's first visit to Durham in the series' history. Following is the complete Challenge schedule: