That didn't happen, though. In fact, he redshirted, and saw no game action.
The following season he seemed to be a candidate to take a vacant cornerback spot or at least some playing time as Ohio State's fifth defensive back, but those roles instead went to classmate Donald Washington and senior former walk-on Antonio Smith.
With the coming of spring practice in 2007, it seemed things would finally be different.
With two full seasons of practice and a spring practice under his belt, Amos was prepared to fight his way into the group of players who would form the 2007 Buckeye secondary.
If told then that he would play in just eight games and be credited for just three tackles, Amos probably would have been surprised and disappointed.
Asked earlier this month to sum up his year, however, Amos had a decidedly different take.
"It's amazing to get back on the field because I was supposed to miss eight months and I cam back in five and a half," Amos said.
The setback was a torn ACL suffered late in spring practice, one that could have knocked him out for all of the following season.
He worked hard and beat that prognosis, however, getting back to health around the start of October. He made his 2007 debut when the Buckeyes beat Purdue 23-7 in West Lafayette on Oct. 6.
"I felt great against Purdue and from there it was no looking back," Amos said.
A week later Amos found himself in the mix with on defense as Ohio State throttled Kent State, 48-3.
"I've had a couple reps with the ones," he said. "That's just amazing. When you have a setback then go back to the bottom and just for my coaches to have that faith and belief in me to step up so fast is quite amazing."
Now he has an eye on making 2008 his year to break through, but waiting his turn has left him with plenty of perspective.
"The biggest thing for me was just learning," he said. "Playing at this level is not that bad. Everybody's talented. We're all on scholarship. The big thing is really buying into the program and system that your team has, your team chemistry. Those are the little things that really add up to being a great player."
Frustrations are inevitable given the level of competition for playing time. Those came for Amos back in 2005 as he was stuck on the bench, but he credited players such as then-Buckeyes Ashton Youboty and Tyler Everett for helping him keep his head on straight.
"They had already paved the way for themselves and they kind of carried me as their little brother so I just learned a lot from them," Amos said.
The coming year figures to be the first in which Amos can rely on both the knowledge gained through experience and the gift of a healthy body. He plans to make the best of both.
"Being a junior next year, I feel that I know the program pretty well and know what the team expects of me," he said.