Senior Marscilla Packer led the Buckeyes in their 72-56 victory with 18 points, five rebounds and three assists.
Jantel Lavender added 13 points and nine rebounds.
Tamarah Riley scored 12 points, one of five Buckeyes to reach double figures, and added six rebounds and three assists.
Shavelle Little scored 11 points and added four rebounds, two assists and four steals.
Ashlee Trebilcock also had 11 points. She added two rebounds and an assist.
Jim Foster's team avenged a loss at Purdue earlier this season.
Alison Jackson had one assist in 14 minutes.