They'll take on No. 4 seed Marist at 7:30 p.m. CT Friday at Marita Hynes Field in the Norman Regional.
That would obviously be in Norman if the Sooners advance because they've earned home field throughout the tournament with their No. 1 seed.
OU has been the consensus No. 1 team in the land for the past nine weeks and ranked atop each of the seven RPI polls over that same time period.
It has never faced Marist but is 4-0 all-time against foes from the Metro Atlantic Athletic Conference.
The Sooners are 2-0 all-time against Fordham and possess a dominant 16-2 all-time mark against Arkansas.