They turned a tight game in the ninth into a no-doubter, racking up six runs to roll out of the Virginia hills for the third time in three trips over the last four years.
And talk about getting hot at the right time, in this game and over the last two weeks.
Two weeks ago today, the Sooners salvaged a crucial series at Kansas State, then ran through the Big 12 Tournament and this weekend's regional unscathed to tally up eight in a row.
That's just the kind of momentum you need heading into a place like Alex Box Stadium and LSU, OU's likely destination.
Should Louisiana-Lafayette come back and top them twice, though, the Sooners would likely host.
As for their late flurry that sealed this one, third baseman Garrett Carey successfully carried out a squeeze play, then left fielder Craig Aikin reached on a bunt single and another scored on it by virtue of an error.
Virginia Tech added one in the ninth, but Aikin made a sliding grab with the bases loaded to end it.
OU actually overcame an early 2-0 deficit that the Hokies compiled heading into the sixth inning thanks to an RBI single off the bat of designated hitter Ryan Burns and a home run from third baseman Andrew Rash.
But OU used a four-run sixth to climb back over the top.
Tournament Most Valuable Player Max White, who hit .500 in the regional with four RBI and three runs scored, might have had his biggest RBI to put OU on the board with a bases-loaded single then.
An error on a ground ball tied it, then Lorenzana gave OU its first lead with his single and another error on Hermelyn's single deep in the hole at short doubled the lead.
Virginia Tech came back with one in the bottom half, but on that play, White came up with perhaps the biggest play of the weekend.
He threw home in time for Lorenzana to tag out the would-be tying runner and preserve OU's edge.
Hero of the last week, reliever Kyle Hayes, then did what he's done over and over the last week, pulling OU out of a two-on, one-out jam in the seventh and they held on from there.
OU has now won seven straight postseason games, and the only years it has compiled longer streaks were in 1951 and 1994, both coincidentally national championship seasons.