Oklahoma, which finished the game with the fourth-most yards in school history (751), posted his highest point total and held an opponent to its lowest offensive output of the season in Big 12 play. The Sooners rushed for 510 yards, the most since 1989, and three different players scored on the ground Saturday.
The Sooners leaned on a simplified game plan, keeping the ball on the ground. Oklahoma (6-2, 3-2 Big 12) punted just once and scored on seven of its first nine drives.
Quarterback Trevor Knight finished with six touchdowns, becoming the first FBS quarterback to throw for three touchdowns and run for three touchdowns in a game this season. He finished with 376 yards of total offense and finished the first half with more than 100 yards rushing, surpassing a career-high early in the second half.
Alex Ross, who also finished with more than 100 yards in the first half, gained 144 yards on 13 carries. Samaje Perine added 110 yards and a touchdown as the Sooners averaged 8.6 yards per carry. Three rushers went over 100 yards for the first time since 1992 for Oklahoma, which became only the second team in the country to reach that mark this season.
Knight threw two interceptions but was able to rebound after losing star receiver Sterling Shepard on the first play of the game – after a 46-yard completion. Knight found seven different receivers in the game. Shepard left the game with a groin injury.
Oklahoma, which had struggled the past three games against quarterbacks with scrambling ability, corralled likely its last mobile quarterback. Iowa State’s Sam B. Richardson rushed for just 20 yards on 10 carries and went 15-for-40 passing.