Ole Miss was actually still in the game in the second half, down only six points at 41-35 after an Eniel Polynice layup. But that was as close as the Rebels would get to the Tigers the rest of the way.
The Rebels, who had 10 different players score in the contest, had trailed 35-23 at halftime.
Ole Miss had an abysmal day shooting in all areas. The Rebels shot 27 percent from the field, 23 percent from 3-point range, and 55 percent from the free throw line.
David Huertas led the way for the Rebels with nine points, and the sophomore guard also had 10 rebounds. Polynice had 12 boards.
LSU, 10-16 overall and 3-9 in SEC action, had four players in double figures, led by Marcus Thornton's 17.
LSU shot 38 percent from the floor, 37 percent from 3-point range, and 82 percent from the free throw line.
The victory was LSU's first at home this Southeastern Conference season. The Tigers' largest lead in the contest was 67-40 with 2:19 to go.
Ole Miss, 18-8 on the season and 4-8 in SEC play, is at Kentucky Wednesday night.
Rebels struggle in loss at LSU
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