Woods, just a junior, already has the school-record for receptions in a career and is eighth in yards.
Lee torched the Ducks defense in last year's win, grabbing eight passes for 187 yards and a score and is fresh off breaking the PAC-12 record for yards in a contest, after racing around the field for 345 against Arizona on Saturday.
Kelly calls them "the best set of wide receivers in the country", and argues that there is little debate against that.
"Everybody knows going into USC you have to stop Woods and Lee," Kelly said Monday. "I don't think anyone has done a good job of that yet. That's a credit to those guys. How talented those guys are."
"Its an art to watch it. All of these athletes running and making plays that you don't see a lot of people make in your lifetime," said senior linebacker Michael Clay.
The Trojans utilize a West Coast underneath passing game that allows Woods and Lee the opportunity to catch it in space and make plays. Because of their elite athletic ability, the Ducks will need to be sure and ready tacklers.
"A lot of the big plays are simple routes, but they're so athletic people miss them," Clay said.
The sophomore Lee in particular is difficult to bring down, Clay says. Kelly attributes that to his "…great change of direction, great vision, great knack for making people miss..."
A highly coveted recruit two years ago, Lee visited Oregon for the Washington game, and was among the star wide-out's finalists.
"We knew he was a really good player, but I don't think anyone could've predicted that as a sophomore he'd have this type of impact," Kelly said.
Defensive coordinator Nick Aliotti recalls that Lee was a top-flight safety prospect as well, ranking third at the position the country that year according to scout.com.
Even then, Aliotti knew he'd never see him on defense if he came to Oregon and the Trojans' decision to play him at wide receiver was apparently the right one.
"…He didn't have to be this good though. Unless he came here," he said.
Last season against USC the Ducks were forced to play then freshmen corners Terrance Mitchell and Ifo Ekpre-Olomu due to the dismissal of Cliff Harris and injury to Anthony Gildon. This year, those freshmen are sophomores, and more equipped to face off against the talented USC tandem, Clay says.
"Now they're all swaggered and they're not going to let anyone get past them."
That can be attributed to experience, Kelly says, also highlighting an increase in strength and confidence as difference-makers.