With Isagawa, sophomore Caroline Inglis and freshman Monica Petchakan in the top 10 of individual standings, the Ducks put two stellar rounds together in New Mexico. Oregon leads third-place UC Davis by three strokes.
Isagawa, a two-time All-Pac-12 selection, leads the field at eight-under with a two-round tally of 138. Her opening round consisted of five birdies and 11 pars, shooting a steady three-under 70. After falling to one-over in her second round, Isagawa lit the course up with six birdies and five pars in the final 11 holes to shoot a 68 (-5), the lowest round of the season by a Duck.
Inglis and Santoso are tied for eighth in the field as both shot identical rounds of 75 (+2) and 71 (-2) to sit at even par through two rounds (146).
Inglis birdies three holes in her first round, but had a streak of four straight bogeys through holes 5-8 to shoot a two-over round. She made par on all four of those holes in the second round, and also made two birdies and 16 pars to card a two-under round.
Santoso played two even-keeled rounds with just five holes over par on the day. She birdied the par-five 18th hole and made 14 pars in the first round to tally a 75. Santoso made birdie on four holes in the afternoon to jump from 24th to eighth on the leaderboard with a 71 (-2).
Junior Monica Petchakan improved three stokes on her opening round and is tied for 51st in the field. Petchakan shot a 79 (+6) in round one with birdies on holes 1, 9, 10 and 13. She carded a three-over 76 in the afternoon with a birdie on the first hole and an eagle on the par-five ninth hole.
Junior Cali Hipp shot a 36-hole score of 163 (+17) and is tied for 82nd.
Senior Raphaela Dyer and freshman Marcella Pranovia competed individually. Dyer is tied for 47th after carding consecutive round of 77 (+4) for a two-round tally of 154 (+8). Pranovia is tied for 59th in the field with a 36-round score of 158 (+12).
Oregon is searching for a consecutive team title at the Dick McGuire Invitational, as the Ducks won the tournament in 2010. Saturday's final round will tee off with a shotgun start at 8 a.m. (PT). Live results can be found at www.golfstatresults.com