Freshman Tyler Dorsey also came up big with 21 points. Elgin Cook added 13 while Chris Boucher was quiet offensively, but did pull down nine rebounds and blocked three shots.
Valpo was led by Tevonn Walker with 14, followed by Alec Peters with 13. Darien Walker had 11 and Shane Hammink added 10.
Oregon shot 44.8 percent from the field on 26-of-528 shooting including 4-of-15 in 3-pointers, plus 17-of-24 from the free throw line. Valpo was 43.3 percent from the field on 26-of-60 with 10-of-32 in 3-pointers and were 5-of-6 in free throws.
The Ducks had a 38-30 advantage in rebounds and a 9-6 edge in steals.
Oregon will next face Arkansas State on Wednesday, Nov. 25, with tipoff at 4 p.m. Pacific. The game will be carried on Pac-12 Networks.