UCLA's first offensive series led to a punt by Aaron Perez after a quick three-and-out. On third down, Oregon safety JD Nelson sacked UCLA quarterback Patrick Cowan for a five-yard loss. Oregon's next drive saw running back Jeremiah Johnson run for two nine-yard gains and a run of the same distance by Dixon. Oregon's seven-play, 55-yard series was capped by a seven-yard touchdown by Johnson to bring the score to 13-0 Oregon with 5:32 remaining.
UCLA retaliated with a 63-yard, 12-play drive to set the score at 13-3 Oregon. Kicker Justin Medlock hit a 33-yard field goal through the uprights to end the drive. On the ensuing kickoff, Jonathan Stewart returned a short kickoff 47 yards to the UCLA 39. After a five-yard run and first down pass to Jaison Williams, Dixon hit Brian Paysinger in the left corner of the endzone for a 26-yard touchdown to up the Oregon lead to 20-3 with 1:01 remaining in the first quarter. Dixon's pass to Paysinger was a replica of the play that gave Oregon the lead and win over Oklahoma on September 16th.
With a rushing attack led by Chris Markey, UCLA then drove 59 yards from their own 20-yard lline. Medlock's 48-yard field goal set the score at 20-6 Oregon with 11:09 remaining in the second quarter. Oregon and UCLA exchanged punts on the next two drives. With time running out in the first half, the Oregon offense went for the first down on 4th and nine. Dixon's throw to Paysinger fell well short, and UCLA's incomplete Hail Mary pass by Cowan was knocked down by Oregon cornerback Jairus Byrd to send both teams into the tunnel. Halftime score Oregon 20, UCLA 6.