Talor Battle also contributed 19 points to help the Lions hold off the Hoosiers 69-60 in front of a wild crowd in Assembly Hall. It marked the second straight victory for the Lions in Bloomington in as many years.
Indiana was attempting to stop a recent skid dropping back-to-back contests, but Verdell Jones' 15 points were not enough for their comeback push as the Lions hit clutch free throws as the game drew to a close.
Penn State was focused on stopping a two-game skid of their own, dropping decisions to Virginia Tech (79-69) and Maine (74-64). Next up the Lions head to Ann Arbor to face the Wolverines on Sunday for a 4:00 pm ET tipoff.
The victory over Indiana marks the fourth time in five seasons that Penn State has won their Big Ten opener.