This will be the third game at Purdue for new head coach Darrell Hazell.
"The energy in Ross-Ade Stadium on the night of September 14th will be awesome," head coach Darrell Hazell said in a statement. "We look forward to hosting an outstanding Notre Dame team and a standing-room-only crowd in The Furnace."
Last season, Notre Dame finished with an undefeated regular season, including a 20-17 win over Purdue, but lost to Alabama in the National Championship. The Fighting Irish have won each game since 2007, a 33-19 Boilermaker win at Ross-Ade Stadium.
It's possible that the in-state rivalry could be coming to an end in 2016 when the Big Ten moves to a nine-game schedule. Purdue athletic director Morgan Burke is working to protect the battle for the Shillelagh Trophy.
This will create some challenges to non conference games already scheduled and we will be working on this issue in the days ahead," said Burke in a statement.
The meeting between Purdue and Notre Dame will be televised on ABC or one of its affiliates. It's possible that more Purdue games will be played at night, as the Big Ten Network has yet to announce its television schedule.