Senior forward Brian Conklin scored just 17 seconds, and the Saint Louis Billikens (10-1) raced out in front 17-0 before the visiting Hornets could get on the board.
"With me and Cody, we can both spread the floor," Loe said. "Then Conklin, Cory, John, and things like that can get inside and get post moves."
After facing several tough non-conference opponents to start out the season, SLU has beaten Portland, UIS, Vermont, and now the Hornets to reach the double-digit win mark.
ASU now heads to Clemson and then Detroit, and have only played one home game in 2011.
"These poor guys have only one game at home," head coach Rick Majerus said. "They've been at Cincinnati, at Evansville, at Florida International."
Loe and Ellis contributed five points each in the first eight minutes of play and Mitchell added eight points of his own in the first 20 minutes. The Billikens defense locked down a Hornets team who came in shooting just 37 percent from the field, holding them to 29 percent in the game and just 11 points in the first half (4-24 FG).
"Our defense really, really helped us today," Loe said.
Freshman Grandy Glaze scored the first points of his SLU career in the second half, and walk-ons Brian Daly and Gus Gehlen made appearances for one of the top teams in the Atlantic 10.
Tonight's defensive output of 35 points for ASU barely eclipsed the record during the Majerus coaching era of 33 points allowed, vs. UMSL. The Hornets were led by Kenderek Washington with 12 points.
SLU now turns their focus to Arkansas State on Dec. 22 at Chaifetz Arena.
NOTES: Mike McCall didn't play due to not meeting academic expectations. Jordair Jett was taken out with a leg injury, but it was only for precautionary reasons, according to a SLU official postgame.