The Wildcats were named the No. 1 overall seed in the Tourney, while the Orange was the second seed in the Big Dance.
North Carolina (Midwest) and Michigan State (West) were the additional No. 1 seeds. The bracket breaks down with Syracuse and North Carolina meeting in a potential Final Four matchup should the top seeds advance.
As for the rest of the East bracket, Syracuse will have to hold off No. 2 seed Ohio State, No. 3 seed Florida State, Fourth-seeded Wisconsin and No. 5 seed Vanderbilt among others including familiar foes Cincinnati (No. 6 seed) and 10th-seeded West Virginia.