Kickoff is at 12:30 p.m. (TV: CSS).
In this week's edition of "Players to watch," InsideTennessee gives you a glance at who will need to be a big part of the game plan in order for their team to get through Week 3 unscathed.
Khalil Mack (sophomore, OLB)
Khalil Mack, based on his play thus far, could have landed in a much more respected program with ease. His is ranked second nationally in tackles for loss with nine.
The 6-foot-3, 248-pounder is the leader of the Bulls defense and has snagged attention from Tennessee head coach Derek Dooley all week.
Other than Mack, there aren't many other players worth keeping your eyes on. Mack is an elite talent, but the Vols should outmatch and overpower Buffalo at almost every other position.
Devrin Young (freshman, RB)
It's what everyone has been waiting for since February of this year — Devrin Young. Tennessee fans haven't seen a punt return go for a touchdown since Mark Jones took one 53 yards to the house against Vanderbilt in 2003.
Young has been the hope of many Tennessee fans since he arrived on campus fresh from Bearden High School. He will get his first shot at punt return and kickoff return this week against Buffalo.
Marlin Lane (freshman, RB)
The freshman tailback has already shown promise in his first three games, but he seemed to have a little extra pep in his step this week during practice. Look for him to come up big in Saturday's game when the Vols desperately try to improve their non-existent running game.
With the running game struggling through the first several weeks, if Lane is able to show he has what it takes you could be looking at the new starter at tailback.
Izauea Lanier (sophomore, CB)
Freshman corner Justin Coleman snagged the start for the Vols' first two games, but Izauea Lanier has taken him over and will get his first start on Saturday.
Lanier proved he can play with talented wide receivers in his appearance at Florida, but it will be important for him to have a good showing in order to solidify his spot opposite Marsalis Teague as the Vols enter the meat of their schedule.