It is the Red Raider's ninth consecutive television game, and this particular matchup is Tech's second opportunity of the season to upset a top-ranked team, after pulling an improbable upset of Oklahoma in Norman just a few weeks ago, but since then the Red Raiders have struggled mightily.
It's also senior day and Texas Tech's Wounded Warrior Project Game.
Last year in its Wounded Warrior Project Game, Tech upset then-No.14 Missouri team, but it won't be easy to slow down Mike Gundy's high-flying offense, but it can be done.
Brandon Weeden, Oklahoma State's 28-year old QB leads the OSU offense.
In 2011, Weeden has completed 282-391 passing attempts for 3,212 yards with 26 TDs and nine INTs.
Sophomore Joseph Randle, a bruising back at 6-1 191 pounds, paces the Cowboys' rushing attack with 151 attempts for 915 yards and 18 trips to the end zone so far. He's particularly effective in the red zone but can bust long runs at times as well.
Backup Jeremy Smith is also a sophomore, and despite not playing last week, Smith has 67 rushes for 502 yards and seven scores this season, completing the one-two punch in the backfield for the Cowboys.
Smith's status for this weekend's game is uncertain, and if he can't go freshman Herschel Sims is next in line with 15 rushes for 126 yards and two scores to finish Oklahoma State's rushing scoring.
Junior Justin Blackmon, who is one of the best-known names on this squad, leads the Oklahoma State wide receiving corps with 87 receptions for 1,039 yards and 12 TDs – this all coming in just nine games.
Other wide receivers to watch include Josh Cooper with 41 receptions for 420 yards and two scores, Tracy Moore with 35 catches for 492 yards and three TDs and Hubert Anyiam with 27 catches for 370 yards and three TDs.
However, Anyiam was lost for the season when he suffered a broken foot on October 22nd against Missouri.
Junior Seth Doege leads the Red Raider offense. In 2011, Doege has completed 294-429 passes for 3,160 yards with 24 TDs and six INTs.
It will be interesting to see which Tech team comes out on the field around Doege. Will it be the one that rallied after being down 20 at Kansas, or the one that has come out flat against Iowa State and Texas?
Eric Ward is Tech's leading receiver, the sophomore from Wichita Falls has 57 catches for 567 yards and nine scores.
Next is Alex Torres with 47 catches for 585 yards and four TDs, and behind him is Cornelius Douglas has 29 catches for 329 yards and one score. However, Douglas is expected to play cornerback Saturday.
Injured star Darrin Moore is next with 29 catches for 388 yards and five TDs, who will most likely play Saturday after logging some time in the loss to Texas with six grabs for 34 yards and a score. When healthy, he's unquestionably Tech's most dangerous offensive weapon.
On paper, this matchup favors Oklahoma State heavily. The Cowboys have a spot in the BCS National Championship within reach.
Win out and Mike Gundy's bunch will play for the title. Stub its toe in remaining games against Tech, Iowa State, and Oklahoma and the title dreams blow away with the Stillwater wind.
Having a 28 year old QB has to help the Cowboys in that regard.
To hang with Oklahoma State's potent offense, Texas Tech has to score early and often.
Oklahoma State's defense is ranked 110th in the country in total yards, giving up an average of 461 yards per game. Conversely, the Cowboys are 2nd nationally in scoring at 50 points per game.
Seth Doege and his teammates are up against the wall, between the pageantry of senior day and the emotionally charged week spent with some of the nation's finest warriors, Tech fans better hope the Red Raiders are inspired to play well.
Oklahoma State: 48
Texas Tech: 20