The first game starts at 3 p.m. today. Game two is Saturday at 3 p.m. and the series finale is Sunday at 1 p.m.
The Raiders bring a 10-4 record into the contest and are on a four-game winning streak. Tech defeated Texas Christian University 10-9 in its last outing Wednesday in Fort Worth.
The contest was the last of an 11-game road swing for the Raiders who last competed at "The Law" in their season-opening three-game sweep of Brigham Young in late January.
Tech shortstop Gera Alvarez went 2-for-3 vs. TCU on Wednesday. He scored three runs and collected two RBI in the win.
Alvarez said after four consecutive road series, the Raiders are happy to be playing in the Hub City this weekend.
"Just being away for so long and all of the sudden getting to come back home can be something awesome," Alvarez said. "It's a good experience to get to compete in front of our home fans."
Seton Hall is not a traditional non-conference opponent for the Raiders, but they schools have played before.
The Pirates claimed a two-game series victory against Tech in 1981 in the only other meeting between the two teams.
Seton Hall qualified for the NCAA Regionals last season and finished the 2001 campaign with a 34-23-1 record.
The Pirates are 2-1 this season, having taken two-of-three games from North Carolina in their first series of the year.
Tech coach Larry Hays said Seton Hall has fared well against Big 12 opponents in the past and is the type of team that will line up and battle against any opponent.
"I guess it was the year before last that they went into Oklahoma State and swept them," Hays said. "They pretty well made a statement that they were looking for games and RPI games and that they would play anyone anywhere. We were able to work it (this weekend's series) out with them."
In Tech's last series, a two-game midweek tilt against the Horned Frogs, the Raiders posted early leads, but staved off late comeback attempts by TCU to claim two one-run victories.
Alvarez said TCU provided the Raiders with an invaluable lesson.
"It just goes to show you that any team can come back at any point," Alvarez said. "We have just got to come out ready to play. We have to come out and give it all we've got the whole game, not wait until the end of the game to try to get on top."