Tech (17-10, 6-6 Big 12) was sharp from 3-point range, hitting 11 of 25, and led by double digits for much of the game. The Red Raiders took their largest lead at 64-38 when Zeno hit two free throws with more than 10 minutes left in the game.
When Plefka got up, the two players almost got into it. The incident brought Tech coach Bob Knight out on the court, walking across the center line to talk with officials after they parted the two players.
Tech fans booed whenever Silas handled or shot the ball the rest of the game.
Jackson-Wilson tried to bring the Buffaloes back, scoring 10 of 12 Colorado points in less than three minutes to whittle the deficit to 71-51 with 8:10 remaining in the game.
Colorado got within 78-63 when Silas hit a 3-pointer with just under five minutes left but the Buffaloes could get no closer.
The Buffaloes went scoreless for about 4 1/2 minutes midway through the first half. During the drought, Texas Tech made field goals on six consecutive possessions, capped by consecutive 3-pointers by Jackson, putting the Red Raiders up 28-16 with 7:38 remaining before the break.
Tech capitalized on Colorado's 11 first-half turnovers, getting 13 points on them.
Tech led 41-30 at halftime.