After the Bulldogs scored the first bucket, Vanderbilt again jumped out to an early lead by playing the inside-out game with Damian Jones.
Jeff Roberson would nail a 3-pointer but it was Matthew Fisher-Davis who would really begin to heat up behind the arc in the first half.
It would seem like all the cylinders were firing as Wade Baldwin IV came away with a steal and added a dunk for emphasis to put Vandy up 20-7.
Fisher-Davis would take over, scoring 14 points in the final 7:09 of first half play. He went into the break with 17 points, shooting 5-of-8 from 3-point range.
Six minutes into the second half with the 'Dores leading by 17 the trouble would begin.
Mississippi State would go on a 26-7 run to bring the game within one point.
Baldwin IV would go inside before dishing it to Jones for a dunk to give the 'Dores a little breathing room.
A lay-up by Bulldog Gavin Ware would pull the game back within one with 41 seconds remaining.
The 'Dores would sub in Riley LaChance, who went 1-of-2 from the free throw line to give Vanderbilt a two point lead.
Mississippi State would badly miss a 3-pointer off the backboard that was unable to be collected by Vanderbilt.
In the ensuing chaos, freshman Quinndary Weatherspoon was found wide open in the corner to hit the game-winning 3-pointer for the Bulldogs.
The Commodores return home to face the (14-10, 7-6 SEC) Georgia Bulldogs on Saturday, February 20th at 11:00 AM CT.