Like so many recent games, the 'Dores got their first points from Damian Jones on a jumper to tie the game at two.
Vanderbilt went on a 10-2 run, starting with a 3-pointer by Wade Baldwin IV and finished on a three-point play by Jeff Roberson.
The Bulldogs tried to trim the lead but Matthew Fisher-Davis and Luke Kornet dropped another pair of treys to put Vandy up by ten.
Freshman Joe Toye put together some nice minutes, shooting 2-for-3 from the field and gave the 'Dores their largest, 16-point lead of the first half with a dunk.
Georgia would whittle away at the lead with a 9-2 run at the end of the half to go into the locker room trailing 37-28.
Vanderbilt would try to force the Bulldogs to stop them inside with a heavy dose of Jones and Kornet who scored the first six points of the second half.
Giving the ball to their big men and driving inside gave them multiple free throw opportunities where they shot 19-of-23 from the line in the second half.
With nine minutes remaining Georgia would twice narrow their deficit to four points before Fisher-Davis dropped a three to start Vandy on a 10-0 run.
Cam Justice would add to the shooting spree beyond the arc and in the final two minutes of crunch time the 'Dores hit their free throws to secure the victory.
Five different Commodores scored in double figures for Vanderbilt.
Next up for the 'Dores is a trip to Gainesville to face the Florida Gators (17-10, 8-6) on Tuesday, February 23rd at 6:00 PM CT.