The game started out as a defensive clinic by Luke Kornet who blocked four shots in the opening five and a half minutes.
Vanderbilt took their first lead of the game on a 3-pointer by Jeff Roberson. With the two teams trading the lead, Wade Baldwin IV found Matthew Fisher-Davis for a beautiful layup.
The Aggies led by as many as nine points before Baldwin IV and Riley LaChance cut into it with a pair of 3-pointers. It was a reemergence of sorts for LaChance, who hit another trey to narrow the deficit to two points.
The 'Dores took a one-point lead on a three-point play by Damian Jones.
Texas A&M would go into the locker room leading 39-32. Things looked grim for the 'Dores who gave up 19 points off turnovers and nine second-chance points. On top of that, Jones and Roberson had three fouls each.
Not even a minute into the second half Jones would have to sit after receiving his fourth foul.
Jones would foul out on a questionable call with nearly 10 minutes left and the Aggies would lead by as many as 20 points with Vanderbilt's leading scorer out of the game.
The 'Dores cut into the lead when LaChance and Cam Justice hit multiple 3-pointers late in the game. LaChance was 3-of-7 from behind the arc and Justice was 2-of-4.
Baldwin IV and Jones led the team at 11 points a piece and Fisher-Davis followed with 10 points.
With the fifth seed the 'Dores will get a one game bye in the SEC tournament before playing the winner of the Tennessee-Auburn game on Thursday in Nashville at Bridgestone Arena.