VU tied a season high with 10 hits on the night.
"I thought the offense was better today," said head coach Tim Corbin. "They still have a ways to go, but it's good to see some hard hit balls. There were a couple of hard hit ones that were caught, but you have to build on something and we will from today."
The Commodores jumped out to a 2-0 lead in the second inning when Matt Meingasner led off with a single to right center and scored on a RBI double by Dominic de la Osa. He then stole third and scored on Parker Hanks' single to left.
The Thoroughbreds cut the lead in half in the fourth, scoring a run on a RBI single by leftfielder Austin Swain off of Vandy starter Ty Davis.
Davis (2-1), who was on a limited pitch count during the game, allowed one unearned run in four innings of work with six strikeouts and two walks.
Cameron Betourne had the best night of his brief Commodore career and picked up his first save in the process. In his first action of the season, he allowed only two hits in five innings of work with eight strikeouts and no walks. The innings pitched and strikeouts were both career highs as he only had three strikeouts in three innings pitched all of last season.
"It was a good feeling to get out there and do well today," said Betourne. "I think establishing my fastball and getting that first strike was the biggest thing in keeping them off base."
"Cameron was very good, he didn't walk anyone and other than the fielding error in the ninth, he did not allow a baserunner after the fifth inning," said Corbin. "He along with Cody Crowell and Ty Davis have all gotten better since redshirting their first year."
The Commodores then put it away in the seventh with three more runs, one coming courtesy of a wild pitch, while the other came on a two-run triple by Alvarez.
Meingasner and Alvarez led the Commodores with two hits each, while rightfielder Brett Mullins led MSU with two hits as well.
"It was important for the team to come out and have a good game today," said Alvarez. "Hopefully we can keep on hitting the ball like we did today and we know it is just a matter of time before it comes around."
Vanderbilt will continue its 14-game homestand this weekend as Ball State comes to town for a three game series. First pitch on Friday is set for 4 p.m., with a 3:30 p.m. start on Saturday and a 1 p.m. start on Sunday. Fans attending the men's basketball game against Tennessee on Saturday can get in for free at the baseball game with their ticket stub.
Murray State 000 100 000- 161 Vanderbilt 020 002 30x- 7(10)2
Harris, Baust (6), Harmon (7) and Payton. Davis, Betourne (5) and Hernandez, Hawkins. W- Davis 2-1, L- Harris 0-1 . SV- Betourne (1). HR- None.