The matchup in the Big Ten/ACC Challenge was sloppy and a struggle offensively at both ends. But Wake Forest (4-0) made enough shots to build an early 11-point lead, increased its margin to 16 at the half and had no trouble holding off the Hawkeyes (4-3) in the second half.
Jamie Skeen added 11 points for Wake Forest, which won on the road for the first time since beating Miami last Jan. 6.
Gaudio succeeded his friend and mentor, Skip Prosser, after Prosser died of an apparent heart attack in July. With Monday's victory, Gaudio became just the third Wake Forest coach to start his career with four straight wins.