Undefeated number one seed Greg Jones lost a 3-2 tiebreaker decision to Ralph Everett of Hofstra, ending Jones' dream of back to back national titles.
The bad streak continued as Ryan Wilman suffered a 15-0 technical fall to Clint Wattenberg of Cornell in the 184 pound weight class.
At 285, Brent Miller received a bye and will face Boise State's Boe Rushton in the second round.
McMath, Jones and Wilman now move to the wrestleback brackets, where they can still earn All-America honors, but can finish no better than third overall.
Action will continue in the evening session, with six WVU wrestlers still alive in the Championship brackets.