Falls hit five threes to lead Notre Dame (12-3, 4-1 Big East) to its eighth win in nine games and its second-best conference start ever. That came on the heels of his six three-pointers in Notre Dame's win over St. John's on Saturday.
Falls' current five-game double-digit scoring streak is the longest of his career.
West Virginia (11-4, 1-3) never had a chance as Notre Dame hit its first seven three-pointers and eight in the first half for a 38-31 lead at the break. Notre Dame, the Big East's best three-point shooting team, buried the Mountaineers on 13 of 25 three-point shooting. It has a school-record 26 three-pointers over two games.
West Virginia leading scorer Tyrone Sally was held scoreless for the first time in his career. WVU was led by Joe Herber's nine points.
It was the first time this season no Mountaineer finished in double-figures.
Notre Dame's largest lead was 59-40 on a Chris Quinn three-pointer with 10:11 left. Quinn had 13 points and Jordan Cornette added a season-high six blocks, all in the first half.
Notre Dame is 11-0 when leading at the half this year and are 21-13 in Big East away games since 2000, the second-best mark in the league. Only Boston College also has a winning league road record in that stretch.
The Irish have a chance to match their best Big East start ever if they can defeat Georgetown and Villanova.
After starting 10-0, West Virginia has lost four of five and three straight.