The Sounds couldn't make it three in a row, getting blasted 10-2 against Round Rock on Saturday night.
Lefty Steve Hammond was rocked in his second start since being promoted from Huntsville, allowing three walks and eight hits, four of them home runs, in giving up eight runs in four innings.
Right fielder Laynce Nix continued his hot streak, slapping his second and third homers in two nights with blasts in the first and third, but Nashville managed only three other hits.
The Stars slipped below .500 at 5-6 with a second straight defeat at Carolina, a two-run eighth the key for the Mudcats' 5-4 triumph.
Nic Ungs, a free agent that Milwaukee signed out of the Florida system in January, allowed one run in five innings. But Mike Jones walked five, allowed three hits and gave up two runs in 1.2 innings. Patrick Ryan didn't fare much better, giving up two hits and two runs, one unearned, to fall to 2-4.
Lead-off hitter and center fielder Freddy Parejo and left fielder Cole Gillespie finished 2 for 4 as the latter clubbed his 10th homer, a solo blast in the ninth. However, Nos. 4-5 hitters Angel Salome and Matt LaPorta finished a combined 0 for 7 with two strikeouts apiece.
The Manatees recently implemented an experiment of starting their relievers before giving way to starters—it didn't work Saturday night during a 5-3 setback to Fort Myers.
Zach Braddock tossed a perfect first but couldn't find his control in the second, walking three, hitting two batters and giving up one hit that led to four runs.
Left fielder Chuck Caufield smacked a two-run homer in the seventh and ended up 2 for 4, first baseman Stephen Chapman swatted his 10th homer in the ninth and right fielder Lorenzo Cain finished 2 for 4 with a double.
Seidel (5-4), a 16th round choice in 2006, allowed only three walks and three hits, a solo homer in the seventh, which knocked Seidel out after 6.2 innings. Frerichs, a 30th rounder in 2007, responded with 2.1 hitless innings for his fifth save.
Outfielder Caleb Gindl smacked a two-run double in the first and designated hitter Eric Farris chipped in an RBI single in the second as part of a 2 for 4 effort. Shortstop and lead-off hitter Matt Cline finished 3 for 4.
The Brewers continued to find ways to win, claiming their third consecutive victory, this one 8-7 against Missoula.
First baseman Brock Kjeldgaard belted a two-run homer, his second, during a three-run first and catcher Corey Kemp chipped in his second, a solo shot in the third. Designated hitter Josh Romanski finished 3 for 4 with a double and third baseman John Delaney chipped in a 2 for 5 performance.
Mark Willinsky, Helena's third hurler, got the win to even his mark at 1-1 after striking out five in three innings. Adam Arnold added two Ks in two innings for his second save as the Brewers' mound staff finished with 12 strikeouts.
The Brewers dropped their fourth contest in five outings as their defense left them early and often during their 11-4 setback to the Mariners. Tony Diggs' squad was charged with eight errors, five of them during a three-run second that ignited the romp.
Milwaukee's team got two hits and an RBI from first baseman Cameron Robulack as the hosts managed only five hits and fanned 16 times.
Righty starter Luis Guerrero (0-1) got the loss, giving up three hits and two walks in 2.1 innings. He allowed seven runs, but only three were earned. Ben Jeffers followed and gave up one run in 2.2 innings but struck out five.