The home run came off Blake Hawksworth (4-4) who had given up just five hits in the first five innings. Portland loaded the bases on a Jarrett Hoffpauir error, and singles from Emil Brown and Chad Huffman.
Chad Huffman led an 11-hit attack with three hits while Craig Stansberry homered for the second straight game.
Tyler Greene, in his second game since being optioned from St. Louis, collected two of Memphis' three hits, stole two bases and turned in two sparkling defensive plays.
The four game losing streak is the longest skid of the season. Memphis is now 1-5 on the current road trip.
Notes: Portland and Memphis combined to steal five bases in the fourth inning; Memphis - Shane Robinson (1), Tyler Greene (2); P0rtland - Emil Brown (1), Chad Huffman (1). Today's Probables: Memphis - RH Mitchell Boggss (0-1, 6.30) Portland - RH Will Inman (0-0, 3.18)