The Cardinals will open the season on the road for the first time since 2006 and fourth time in the last 11 years when they visit divisional foe Cincinnati on Monday, April 5 (12:10 p.m. CDT). It marks the 17th time the Cardinals will meet the Reds in the season opener and the first time since 1994 at Cincinnati.
The Cardinals home opener will be on Monday, April 12 (3:15 p.m.) against the Houston Astros, the first of three games in four days against their division rival.
St. Louis does not face the Chicago Cubs until Memorial Day weekend in a three-game series at Wrigley Field. The Redbirds do not host the Cubs at Busch Stadium until the season's second half, a weekend series in mid-August (Aug. 13-15). St. Louis will face Chicago nine times in the season's final two months, with their second and final meeting at Busch from September 13-15.
The Cardinals meet in-state, interleague rival Kansas City only on the road this season (June 25-27), after home-and-home interleague tilts with the Royals the last four seasons. The other interleague road series will be at Toronto, just prior to the Kansas City stop.
The A.L. West is the primary division the N.L. Central will meet in interleague play, with the Los Angeles Angels (May 21-23), Seattle Mariners (June 15-17) and Oakland Athletics (June 18-20) all set to visit Busch Stadium in 2010.
The Cardinals play 42 games at home prior to the All-Star break and 39 after the break. The team will wrap up the 2010 season with 17 of their last 30 games at home, including two seven-game homestands, the last of which will close out the season against Pittsburgh (3) and Colorado (4).
The Cardinals will have future announcements concerning ticket pricing, availability and broadcast schedules for 2010.