"We didn't hit a ball hard," Manuel said. "We didn't get nothing going. I think Garza had a lot to do with it, but our hitting is inconsistent and we have to be more consistent."
"You have to hit some balls hard to win games. I feel like we're treading water. We have to play a lot better," he said.
Philadelphia looked to be snapping out of its season-long funk at the plate last week when it scored 20 runs in winning two out of three at Arizona. But the Phillies have generated just seven runs in losing two of three thus far in this four-game set.
"We definitely didn't get after him," Manuel said of Garza. "We showed we can look like a pretty good team, but today we were pretty inconsistent and fall back."
Minus their two key bats, Phillies hitters may be pressing some.
"At times everyone is trying too hard," said Laynce Nix, who went 0 for 3 while taking Howard's spot at first base. "We're all trying to get it doing and make a difference."
Garza (2-1) gave up a pop-fly single to Jimmy Rollins leading off the first and nothing more.
Rollins was back batting leadoff after being inserted into his usual spot in the order for the first time this season on Saturday. He struggled filling the No. 3 hole vacated by Utley and is hitting .222 on the season.
Garza retired 20 of the next 21 batters, with Juan Pierre's seventh-inning walk accounting for the only other baserunner.
"I just stuck to the game plan, keep them off-balance and try to get popups or groundballs," Garza said. "I was very comfortable out there. I wanted to go after them. They're a very aggressive team."
Besides Rollins' single, the Phillies didn't have anything even close to a hit off Garza, who was lifted after 103 pitches.
"He was dominating," Cubs manager Dale Sveum said.
Mather's homer was the first by a Cubs outfielder this season.
"That's a crazy fact," Mather said.
"It's early. We've been through this before and the bats came through," Kendrick said.
The Cubs took a 1-0 lead in the second on Ian Stewart's groundout that scored LaHair. Chicago could have tallied more, with runners on second and third with one out, but Kendrick struck out Welington Castillo and Garza to escape further trouble.
Chicago tacked on a run in the third, thanks to the speed of Campana. After he singled, Campana went to second when Nix failed to catch Kendrick's throw on a pickoff attempt, then to third on Darwin Barney's groundout.
Campana scored on Starlin Castro's fly ball to medium right field, just beating the strong throw of Pence. Manuel came out to argue the safe call of plate umpire Bill Miller, but replays appeared to confirm the call was correct.
Mather's line-drive homer to left with two outs in the fourth put Chicago up 3-0.
Campana's speed showed up again in the eighth when he reached on an infield single, stole second went to third on a sacrifice bunt and scored on Castro's grounder that didn't even reach the infield dirt.
NOTES: The crowd of 45,550 was Phillies' 229th straight sellout, including postseason play. ... Wigginton went 0 for 3, ending his 13-game hitting streak.