Hideo Nomo was roughed up in the first inning when he allowed a two-out double and a home run.
He gave up two more in the third but a mis-fired throw on a double play attempt could have resulted in a scoreless inning.
Darren Dreifort, Paul Shuey, Tom Martin and Agustin Montero added one-inning zeros to the board. Jason Frasor gave up a run when the Dodgers mis-handled a double-steal in the seventh inning.
Isturis collected the Dodger RBI in the fifth, following singles by Jose Hernandez and Wilkin Ruan.
VOlmedo Saenz and Willie Aybar added singles during he game and Franklin Gutierrez collected a double.
The loss was the first on a two-day road trip to Ft. Myers, a three-hour bus ride from Dodgertown.
Dodgers go quietly in Ft. Myers
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