Lowe retired 11 straight batters at one point, but gave up a two-run homer in the first inning and struggled through a four-run fifth inning that cost him and the Dodgers the game.
Arizona starter Livan Hernandez earned the win but the DBacks to battle to hold their 8-1 lead in front of 52,921 at Dodger Stadium.
Los Angeles fell to 58-52, the first time they have been no more than six games over .500 since May 22, and are now three games behind the DBacks, their biggest deficit of the season. They have lost 11 of their past 17 and haven't won a series since taking two out of three against Philadelphia at home July 16-18. in mid-July.
Lowe's last win was June 22 at Tampa Bay. On Saturday, he gave up only four hits and walked one but left with the Dodgers trailing 6-1. The deficit ballooned to 8-1 following a two-run homer by catcher Miguel Montero off Houlton.
But unlike the first game of the series, the Dodgers managed to rally, scoring on Andre Ethier's sac fly in the sixth and in the seventh inning, Rafael Furcal and Juan Pierre, who had two hits, got back-to-back singles, followed by an error by the Arizona right fielder to load the bases. Luis Gonzalez hit a sacrifice fly to left, scoring Furcal and cutting the lead to five before Nomar Garciaparra slugged his sixth homer, his fourth since July 20th.
Ethier made it 8-7 in the eighth with his ninth home run off of Arizona reliever Tony Pena but that was it for the offense.
The Diamondbacks got a run in the fifth inning on an error by first baseman James Loney, another when Justin Upton slid just below Russell Martin's tag at home and a third when the Dodgers couldn't turn a double play in time to get Byrnes at first on a grounder.
The Dodgers loaded the bases with two outs in the fourth inning but managed only a run. Hernandez walked in Pierre, then got out of it by getting Ethier to ground out. The Dodgers again trouble driving in in runs, leaving five in scoring position.
Lowe's didn't help him much. In the fifth inning, Loney made a stop on a ground ball to his right but threw low to Lowe who was covering first, allowing a run to score and the runners to advance to second and third with no outs. That error led to a four-run fifth inning and put the Dodgers behind, 6-1, and they never fully recovered.
Hoping to avoid a sweep, the Dodgers send Brad Penny (13-2, 2.60 ERA) to the mound against Arizona ace Brandon Webb (10-8, 3.08) this afternoon in the final game of the series at Dodger Stadium.
Score by innings Arizona 200 042 000-8 Los Angeles 000 101 410-7 Los Angeles ab r h bi ave Furcal ss 5 1 1 0 .287 Pierre cf 4 2 2 0 .279 Martin c 5 1 0 0 .294 Gonzalez lf 3 0 1 0 .283 Garciaparra 3b 5 2 2 3 .285 Loney 1b 3 0 1 0 .331 Martinez 2b 3 0 0 1 .176 Ethier rf 3 1 1 2 .300 Lowe p 1 0 0 0 .154 Young ph 1 0 1 0 .200 Houlton p 0 0 0 0 .000 Kemp ph 1 0 0 0 .328 Seanez p 0 0 0 0 .000 Broxton p 0 0 0 0 .000 Saenz ph 1 0 0 0 .176 Saito p 0 0 0 0 .000 Totals 35 7 8 7 Arizona 39 8 10 7 Error- Loney (8). HR- Garciaparra (6), Ethier (9). RBI- Martinez (12), Ethier 2 (46),Gonzalez (52). Garciaparra 3 (57). SF- Ethier, Gonzalez. :OB- Los Angeles 7, Arizona 5. Los Angeles in h r-er bb so era Lowe (8-10) 5.0 4 6-4 1 4 3.58 Houlton 1.0 2 2-2 0 1 5.17 Seanez 1.0 1 0-0 0 1 .403 Broxton 1.0 1 0-0 0 1 2.56 Saito 1.0 2 0-0 0 1 1.48 HBP- Gonzalez, Pierre. T- 2:55. Att- 52,921.Dodger Blue Notes-- Manager Grady Little noted after the game, "When you're going through a spell like we're going through right now, it's a total team effort. We left a little bit with our pitching, we've left a little bit with our offense, we've left a little bit with our defense, and it all works together. It's all part of what it takes to play not winning baseball. I got deep concern in all the areas I just talked about, but we just have to keep working and get turned around. We have a lot of time left." ...Outfielder Delwyn Young made his first career start on Friday night and got his first major league hit last night as a pinch-hitter. Young hit .343 with 16 home runs and 79 RBIs at Triple-A Las Vegas before being called up on July 31. ...Jeff Kent missed his fifth straight game with a strained hamstring after hitting .650 on the club's recent road trip. ...Barry Bond' hit his record-tieing home run in San Diego and Alex Rodriguez finally it his 500th homer. ...Lowe has allowed 13 unearned runs, the most on the Dodgers' staff and four more than he did last year. He has not reached the sixth inning in any of his last four starts. ...Jonathan pitched a scoreless eighth inning, striking out one batter and lowering his season-ERA to 2.56. Broxton has not allowed a home run since July 24, 2006, a span of 87.1 innings, which represents the second-longest current homerless streak in baseball. The big right-hander also lowered his ERA to 1.34 (5 ER/33.2 IP) at Dodger Stadium in 32 appearances.has not allowed a homer in 87 games, surpassing former Dodger Gregg Olson (1989-90) for the 10th longest streak in baseball since 1957. ...Last night's crowd was the Dodgers' 23rd of the season with 50,000 or more in paid attendance.