Hiroki Kuroda (1-3), who hasn't won since opening day, allowed five runs and seven hits over six innings, including a pair of home runs, before he was lifted for a pinch hitter.
The Dodgers, trailing 5-2, cut the As lead in the seventh on Ethier's two-run single with one out but an inning-ending double play killed the rally.
Manager Joe Torre said. "We had opportunities, no question. They gave us extra outs, but unfortunately we couldn't get the big hit."
The Athletics tagged Kuroda for three runs and a 4-0 lead in the third inning. A home run, a single by Cahill, his first at-bat in over three years, and a second home run did the damage and Oakland their lead to 5-1.
Matt Kemp singled in the second and stole second and third but was left on base. Eleven straight batters went out in order before the Dodgers, trailing 4-0, scored their first run in the fifth on an RBI single by Hudson after Pierre had doubled and Rafael Furcal lived on a two-out error by the Oakland second baseman.
They added a second run in the sixth when Blake lived on an error, Ethier doubled and Kemp hit a sac fly. Martin walked but pinch-hit Mark Loretta struck out and Pierre bounced to first.
For Loretta, it was his 14th consecutive hitless pinch-hitting attempt after collecting eight hits in his first 13 appearances.
The final two runs came in the seventh when Furcal led off with a walk and Hudson was safe when the Oakland right fielder dropped his fly ball. Loney popped out, Blake singled to left to load the bases and Ethier added his second hit of the day, pulling the Dodgers to within one run before Kemp hit into a killing double play.
Pinch-hitter Mitch Jones got his first major league hit with one out in the eighth but this time it was Pierre who hit into an inning-ending double play.
Hope flickered for a moment in the last of the ninth when Furcal led off with a single but it quickly died when Hudson, Loney and Blake went out in order.
Brent Leach, Guillermo Mota and Ronald Belisario completed the final three innings, allowing a pair of singles and no runs.
Ether was the only Dodger with more than a single hit.
Kuroda hasn't had much run support after winning the opening day game 5-1. While is 0-3 in June after coming off the disabled list, the Dodgers have scored only twice while he was in the game.
Kuroda hit 95 mph on the gun this night and afterwards said, "I don't think my physical condition is bad," Kuroda said. "I have all my pitches. I haven't had any luck and I mislocated pitches. I just have to be patient and wait for the game I pitch well and win at the same time."
"He was trying to overthrow the ball," Dodgers manager Joe Torre said. "He was like trying to throw the ball through a wall. The home runs were in the middle of the plate. He will gradually get back to where he gets the feel."
RHP Jeff Weaver will start Saturday against younger brother Jered when the Dodgers face the Angels in Anaheim. It will be the 21st time in major league history that siblings will start against each other and the first time since Sept. 6, 2002, when the Cardinals' Andy Benes handed the Cubs and younger brother Alan an 11-2 defeat at St. Louis. Weaver will be filling in for Eric Milton, who is healed from a strained back muscle that put him on the disabled list. But Milton cannot be activated until Sunday. Torre told Weaver to throw a bullpen session during Wednesday night's game, as long as starter Hiroki Kuroda did not leave the game early. "It's a chance to share the same mound on the same day and not many can say that," said Weaver. "It's a moment we won't forget. It's pretty special regardless of the outcome." Jeff said his parents had planned to attend the wedding of a relative in Temecula, Calif., but those plans have changed. "I wouldn't want to be the people sitting around them during the course of the game," he said. "The best way I can explain is both of us coming out of the game tied and leaving it up to the bullpens to decide the game."
Matt Kemp's RBI-single in the 10th inning in the first game of the series gave the Dodgers their eighth walk-off win of 2009, which matches their 2008 season total. Since the start of 2008, their 16 walk-off victories are tied with the New York Yankees for the most in baseball during that time. Here is a list of the club's 2009 walk-offs:
Date Opp Score Winning Play April 15 SF 5-4 Loney walk (9th) May 1 SD 1-0 Martin walk (9th) May 2 SD 2-1 Ethier single (9th) May 18 NYM 3-2 Hudson fielder's choice (11th) May 23 LAA 5-4 Pierre walk (10th) June 5 PHI 4-3 Ethier double (9th) June 6 PHI 3-2 Ethier homer (12th) June 16 OAK 5-4 Kemp single (10th)Dodgers Blue Notes-- Dodgers closer Jonathan Broxton received a cortisone shot in the big toe on his right foot and wasn't available to pitch. ...Catcher Russell Martin was 0-for-3 and is 5-for-43 (.116) in his last 12 games. ...Randy Wolf is undergoing medical tests to determine if whooping cough is the source of his persistent cough. Wolf has been bothered by the cough for about six weeks. He said he feels fine otherwise and believes it has no effect on his pitching. "It's been nagging and it's something more than a cold," said Wolf. "It really doesn't affect me. It just gives me a sexy voice." ...Torre said injured reliever Will Ohman, who is on the 15-day disabled list, will make his second rehab appearance for Triple-A Albuquerque on today and will pitch in back-to-back games next week before being activated. ...Claudio Vargas continues to recover from a torn elbow tendon, and Torre said he most likely will be kept in relief when he returns. ...Jason Schmidt might make another rehab start in a few days but Hong-Chih Kuo still isn't ready for one yet. ...The Dodgers continue their stretch of 15 straight Interleague games (3-1) by playing the final game of a three-game set with the Oakland A's tonight. Then the club will head out for a six-game road swing against the Angels and White Sox, before retuning to Los Angeles on June 26 to take on the Mariners. ...The Dodgers have the best record in baseball at 43-23 (.652), 2.5 games over the Boston Red Sox (40-25, .615). Los Angeles has won three straight games, six of their last ten, and eight of their last 13.