The big inning came back to bite the Cleveland Indians for the second time in as many days.
In what appeared to be a pitcher's duel through the first five innings, the Arizona Diamondbacks were able to break a 1-1 deadlock with a five-run sixth to roll over the Tribe by a score of 11-2 on Saturday night at Chase Field.
Trevor Bauer matched Zack Greinke inning-for-inning until he surrendered three extra-base hits to the meat of the D-backs order in the decisive frame.
More on Bauer
Similar to Josh Tomlin's start on Friday, Bauer was smooth sailing his first two times through the opposing lineup. Arizona mustered four hits in its first 18 at-bats and could not capitalize with runners at the corners and two outs in the second inning.
The tables turned in the sixth when David Peralta homered, Paul Goldschmidt doubled and Yasmany Tomas tripled to yield a 3-1 advantage.
"That third time through, once they get going, they get real aggressive," said manager Terry Francona to reporters. "I thought Trevor was really throwing the ball well. You looked up in the fifth, Greinke and Trevor were identical."
Bryan Shaw entered in relief of Bauer and allowed two of his inherited runs to score on Brandon Drury's RBI double and Jeff Mathis' RBI single. Eleven of the home team's hits came after the fifth inning.
"It just got away from us in a hurry," Francona said. "When they get aggressive and they start feeling good - we've seen it two days in a row now - they put a [hurting] on us in a hurry."
For the series, the D-backs have registered eight runs with two outs.
With the game already out of reach, the Cleveland relief unit gave up six more scores in the eighth inning alone.
Going up against Boone Logan and Shawn Armstrong, Arizona tallied six hits and batted through its lineup to bring each hurler's earned run average to 13.50 and 15.00 respectively.
Santana scores run on birthday
Offense came at a premium for the Indians as they batted around the Mendoza Line (7-for-33, .212) for the second consecutive contest. Now 31-years-old, Carlos Santana doubled and scored the game's first run courtesy of Michael Brantley's one-out RBI single.
Santana entered play with at least one RBI in each of his first four games of the season, a franchise feat that was last achieved by Victor Martinez in 2006. In addition, the Dominican native is hitting .400 (14-for-35) with six home runs and 16 RBIs on his birthday, according to MLB.com's Jordan Bastian.
Jose Ramirez knocked in Francisco Lindor (single) on a RBI double in the ninth to conclude the road affair.
The Indians wrap up their six-game road trip on Sunday at 4:10 pm ET from Chase Field in Phoenix, Ariz
Corey Kluber (0-0, 7.50) and Patrick Corbin (0-1, 4.50) are scheduled to make their second starts of the season in the matinee.
John Alfes has covered the Indians for IBI since August of 2016. Follow him on Twitter @JohnAlfes for breaking news and in-depth coverage all season long.