Mets' (16-21) starter Pedro Astacio went six innings and surrendered seven hits, two runs, and three walks while fanning three. Graeme Lloyd (1-0) worked two scoreless innings to get the win before Armando Benitez worked out of trouble in the ninth to earn his eleventh save.
The Padres (12-25) got on the board in the top of the first after the first two batters, Ramon Vazquez and Keith Lockhart, singled to begin the game. Ryan Klesko doubled to drive in one run before Rondell White hit a sacrifice fly to give San Diego a 2-0 lead.
Cliff Floyd cut the margin in half in the second when he hit his fifth home run of the season, a solo shot off Padres' starter Jake Peavy.
Jake Peavy, who threw 126 pitches, went 6 1/3 innings allowing seven hits, two runs, and five walks while striking out six. Mike Matthews (1-1) took the loss after throwing the wild pitch that allowed Roger Cedeno to score in the eighth.
The Mets placed RHP Scott Strickland on the 15-day disabled list after he suffered a groin strain during Saturday‘s game and called up LHP Jaime Cerda from Triple-A Norfolk... Joe McEwing started again at short stop , with Rey Sanchez suffering from a sore elbow, and went 0-for-4... RHP David Cone made his first rehab start with Class A St. Lucie and allowed one run and five hits while striking out two and walking one over four innings... Steve Trachsel (0-2, 4.95) draws Jason Young (First ML start) on Monday in Colorado...