Mikolas went 2-1 with a 3.62 ERA across 25 games with the San Diego Padres. In 32.1 innings he allowed 32 hits, hit two batters and walked 15 while striking out 23. He inherited 19 runners, six of which scored.
Mikolas went 2-1 with a 3.20 ERA across 17 games for the Triple-A Tucson Padres. In 19.2 innings he allowed 20 hits and eight walks while striking out 18. Two of the three runners he inherited scored.
Mikolas went 1-1 with four saves across 12 games for the Double-A San Antonio Missions. In 12.1 innings he allowed 16 hits and walked three while striking out 11. Of the two runners he inherited one scored. He also induced three double play grounders.
Mikolas went 0-0 with three saves and a 7.15 ERA across 11 games in the Arizona Fall League. In 11.1 innings he allowed 16 hits and four walks while striking out 10.
Mikolas went 1-0 with nine saves and a 1.67 ERA across 28 games with the Double-A San Antonio Missions. In 32.1 innings he allowed 29 hits and six walks while striking out 27. He stranded both runners he inherited and induced two double play grounders.
Mikolas went 3-0 with 12 saves and a 1.13 ERA across 34 games with the High-A Lake Elsinore Storm. In 39.2 innings he allowed 31 hits, hit three and walked nine while striking out 42. He stranded nine of the 11 runners he inherited, limiting the opposition to a .136 average with runners in scoring position.
Miles Mikolas was named to the Midwest League mid-season All-Star team due to an injury to another pitcher. He retired the only batter he faced.
Miles Mikolas went 6-3 with a 2.20 ERA across 60 games with the Fort Wayne TinCaps, earning 13 saves. In 82.1 innings, he allowed 76 hits, walked 15 and struck out 78. He held the opposition to a .238 average. He allowed 3 homers, did not hit a batter, tossed 6 wild pitches, and had a 73.7 left on-base percentage.
Miles Mikolas went 1-8 with a 5.94 ERA across 15 games, including 11 starts, with the Eugene Emeralds. In 53 innings, he allowed 77 hits, walked nine and struck out 39. He held the opposition to a .332 average. The opposition stole seven bases off him in nine attempts. He allowed one homer, hit five batters, tossed three wild pitches, and induced seven double play grounders. The opposition hit .329 off him with runners in scoring position in 70 at-bats. Mikolas led the Northwest League in losses.
Miles Mikolas was selected in the seventh-round with the 204th overall pick by the San Diego Padres.
Mikolas led the squad with a 2.06 earned run average while going 7-2 in 83.0 innings pitched. He threw four complete games, including two shutouts, in 11 starts. Mikolas is among the national leaders with 80 strikeouts to just eight walks on the season. He pitched a complete game three hit shutout at St. Thomas and a four hit complete game shutout at Rollins. He has been selected on three post season teams, 2nd team All-Sunshine State Conference, ABCA/Rawlings All-South Region and 2nd team DAKTRONICS All-South Region.