"It's another challenge for us, especially the secondary," Bears cornerback R.W. McQuarters said. "I said last week, when everybody was talking about TO (Terrell Owens), (the media) asked me who is more explosive? It's Randy Moss, in my opinion.
"If you sleep on him, he'll go right by you and you'll get beat. You've always got to be alert. You've got to stay awake."
Moss, who had nine catches for 150 yards and a touchdown in last week's 30-25 over the Packers in Green Bay, has feasted on the Bears and the rest of the NFC Central/North. In 39 games in the division, Moss has 212 catches for 3,700 yards and 31 TDs.
Last time out against the Bears, Moss had nine catches for 119 yards and a touchdown in the Vikings' 25-7 win on Oct. 27, 2002 at the Metrodome, the site of tonight's game at 7:30 p.m.
In 10 games against the Bears, Moss has caught 62 passes for an average of 14.1 yards per grab with seven TDs.
"I get asked every year if Moss is the biggest challenge," Bears cornerback Jerry Azumah said. "He's a great athlete. He's big, he's fast and he's explosive. We know what he can do when he's got the ball in his hands.
"It's going to be a great challenge for our defense to take him out of the mix."
Culpepper, who threw for three touchdowns and ran for another in the win over the Packers, is equally dangerous in or out of the pocket. In six games against the Bears, Culpepper has completed 62 percent of his passes, thrown six touchdowns, rushed for an average of 4.7 yards a carry and scored three TDs. Culpepper's quarterback rating against the Bears is 83.6.
"They have the big weapons with Moss and Culpepper," Bears defensive coordinator Greg Blache said. "We've just got to approach this game as an opportunity to go and get things back on the right track."
The Bears offense, which was horrendous in last week's 49-7 loss at San Francisco, will have to overcame an inexperienced offensive line in a very loud environment at the Metrodome, arguably the loudest stadium in the NFL. Newly signed Bears guard Corbin Lacina, who played four seasons in Minnesota including 16 starts last season, knows the Bears' offensive line will have its hands full. He said the Vikings watched the 49ers tape and saw the success they had blitzing Chicago.
"It's a copy-cat league. Guys will try to do the same thing, I'm sure," Lacina said. "Of course they looked really good against Green Bay, so they might bring out the same kind of defense, too. Either way, it's a tremendous challenge because of the environment.
"It's a very hostile environment, it's loud and it really suits their style of play."