Nigel Bradham's absence will open the door for rookie linebacker Tony Steward. This will be Steward's first career start. Mario Butler will be inactive on Sunday. He was picked on last week by Alex Smith when Ronald Darby exited the game for a short period. New addition Lavar Edwards won't suit up on Sunday for Buffalo.
On the offensive side of the ball, Seantrel Henderson will miss today's game. He'll be replaced by Jordan Mills. Expect Mills to get a lot of help on Sunday against J.J. Watt. Karlos Williams is out for today's contest and the Bills will depend upon LeSean McCoy, Boobie Dixon and Mike Gillislee. At right guard, Kraig Urbik will start in place of rookie John Miller. Urbik has fared well as of late but today will be a tough test for the reserve lineman. Last, third string quarterback Josh Johnson is inactive on Sunday.