Hoyer was informed by Rob Chudzinski that he will get the start in place of Brandon Weeden, who left Sunday's game with the Ravens with a thumb injury. No indication on how long Weeden is expected to be out.
Hoyer was inactive for the first two games and has been third on the team's depth chart throughout the preseason.
Chudzinski said Monday that he wanted to keep all of his options open.
"I'm going to keep all of our options open right now," he said Monday when asked who would start if Weeden couldn't. "We're really waiting on Brandon to see where he's at and make the determination in the next few days."
Jason Campbell relieved Weeden against the Ravens for one series and was 1-of-4 for 6 yards. He has a 31-40 record as a starter in the NFL.
Hoyer started one game in his NFL career. Last year as a member of the Arizona Cardinals, he started against the San Francisco 49ers. Hoyer finished 19-for-34 for 225 yards and a touchdown and an interception.
Hoyer grew up in North Olmstead and played at St. Ignatius before playing college football at Michigan State.
Chudzinski is expected to address the topic in his press conference later Wednesday morning.