Quarterback Derek Anderson is a career 53 percent passer, and it's going to be difficult for him to improve much, given the team's injuries at receiver.
Larry Fitzgerald is less than 100 percent because of a sprained knee ligament suffered in the preseason. Early Doucet, the No. 3 receiver, suffered a groin injury against the Rams, and his status likely will be at least questionable all week.
That leaves Anderson with three healthy receivers: Steve Breaston, a reliable starter, and rookie free agents Max Komar and Stephen Williams.
Anderson has struggled with accuracy throughout his career, and having two inexperienced receivers among his top four won't help.
"It was difficult," coach Ken Whisenhunt said after the Rams game, "and Larry, as the game went on, his knee started to bother him and it slowed him down some. So we got new guys playing different spots, who have never played in a game."
Anderson tried to go to Fitzgerald, targeting him 15 times. He completed only three. Fitzgerald didn't create his usual separation, but there were times where Anderson just plain missed him.
If that happens against better teams than the Rams, the Cardinals will lose.
Injuries at wide receiver hurting Anderson
CardinalsSource Top Stories
Upon further review: Palmer's interceptionsThis week's 'Upon further review' for the Cardinals' offense analyzes Carson Palmer's four interceptions and what went wrong.
CardinalsSourceYesterday at 4:49 PM
Palmer disappointed in his own performanceThe Arizona Cardinals' quarterback was hard on himself after Sunday's game, but said he knows there's a lot of football left to be played.
CardinalsSourceYesterday at 9:06 AM
Arians calls Sunday worst start in four yearsThe Arizona Cardinals were trounced by the Buffalo Bills by a final score of 33-18 to drop their second contest of the season Sunday.
CardinalsSourceYesterday at 8:12 AM
Instant analysis: Slow start dooms ArizonaThe Arizona Cardinals suffered through a dismal start on offense in the team's first road trip of the season.
CardinalsSourceSunday at 11:43 AM