Blessed with a two-game lead in the AFC West with just five remaining contest - three of which are at home - the Chargers are fairly certain their second playoff appearance since 1995 is on the horizon.
But first is a pesky Bills team that dropped the Jaguars on Sunday and are feeling good about themselves with the return of Willis McGahee.
"Not that we're looking ahead but as you looked at the schedule you sense this was going to be a big game and a tough game," quarterback Philip Rivers said of the Sunday date at Ralph Wilson Stadium. "This (would get) us to 10 (wins).
"Does that mean you relax? Not at all, because you're never in until you're in, and there's still more to play when you're in. But getting to 10 would be huge and then having three of four at home."
The Chargers aren't home free yet, but there is a sense this season will certainly expand past the regular-season finale against the visiting Cardinals.
"As it gets closer and the season comes down you start to think more about it," running back LaDainian Tomlinson said. "I don't care what anyone tells you, you think, 'Can it happen?' I'm certainly thinking about it.
"We're not going to get ahead of ourselves, but I'm just saying we're 9-2 and fighting for a bye."
First they have to say hello to a cross-country trip and a game in which weather could be a factor with snow flurries expected for Sunday.